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Accounting System of Scientific Activity (ASSA)

      

Yakov Tsepilov

Department: Laboratory of Recombination and Segregation Analysis
Pluralist: Kurchatov Genomic Center of the Institute of Cytology and Genetics of the Siberian Branch of the RAS
Room: Дистанционная работа
Email: tsepilov@bionet.nsc.ru


Personal information

https://publons.com/researcher/1404593/yakov-a-tsepilov/



Publications

2023 Population Structure and Genetic Diversity of the 175 Soybean Breeding Lines and Varieties Cultivated in West Siberia and Other Regions of Russia
Nadezhda A. Potapova, Alexander S. Zlobin, Roman N. Perfil’ev, Gennady V. Vasiliev, Elena A. Salina, Yakov A. Tsepilov
[Plants]
Multivariate Genome-Wide Association Study of Concentrations of Seven Elements in Seeds Reveals Four New Loci in Russian Wheat Lines
Nadezhda A. Potapova, Anna N. Timoshchuk, Evgeny S. Tiys, Natalia A. Vinichenko, Irina N. Leonova, Elena A. Salina, Yakov A. Tsepilov
[Plants]
Loci Associated with Negative Heterosis for Viability and Meat Productivity in Interspecific Sheep Hybrids
Alexander S. Zlobin, Natalia A. Volkova, Natalia A. Zinovieva, Baylar S. Iolchiev, Vugar A. Bagirov, Pavel M. Borodin, Tatiana I. Axenovich, Yakov A. Tsepilov
[Animals]
Multi-Trait Exome-Wide Association Study of Back Pain-Related Phenotypes
Zorkoltseva IV Elgaeva EE Belonogova NM Kirichenko AV Svishcheva GR Freidin MB Williams FMK Suri P Tsepilov YA Axenovich TI
[Genes]
2022 Noncoding rare variants in PANX3 are associated with chronic back pain
Nadezhda M Belonogova, Anatoly V Kirichenko, Maxim B Freidin, Frances M K Williams, Pradeep Suri, Yurii S Aulchenko, Tatiana I Axenovich, Yakov A Tsepilov
[PAIN]
Causal effects of psychosocial factors on chronic back pain: a bidirectional Mendelian randomisation study
Frances M K Williams, Elizaveta E Elgaeva, Maxim B Freidin, Olga O Zaytseva, Yurii S Aulchenko, Yakov A Tsepilov, Pradeep Suri
[EUR SPINE J]
Genetic regulation of post-translational modification of two distinct proteins
Arianna Landini, Irena Trbojević-Akmačić, Pau Navarro, Yakov A Tsepilov, Sodbo Z Sharapov, Frano Vučković, Ozren Polašek, Caroline Hayward, Tea Petrović, Marija Vilaj, Yurii S Aulchenko, Gordan Lauc, James F Wilson, Lucija Klarić
[NAT COMMUN]
A novel framework for analysis of the shared genetic background of correlated traits
Gulnara R Svishcheva, Evgeny S Tiys, Elizaveta E Elgaeva, Sofia G Feoktistova, Paul RHJ Timmers, Sodbo Zh Sharapov, Tatiana I Axenovich, Yakov A Tsepilov
[Genes]
A protocol for recruiting and analyzing the disease-oriented Russian disc degeneration study (RuDDS) biobank for functional omics studies of lumbar disc degeneration
Olga N. Leonova, Elizaveta E. Elgaeva, Tatiana S. Golubeva, Alexey V. Peleganchuk, Aleksandr V. Krutko, Yurii S. Aulchenko, Yakov A. Tsepilov
[PloS One]
In silico genome-wide gene-based association analysis reveals new genes predisposing to coronary artery disease
Zorkoltseva I, Shadrina A, Belonogova N, Kirichenko A, Tsepilov Y, Axenovich T.
[CLIN GENET]
Mendelian randomization analysis of plasma levels of CD209 and MICB proteins and the risk of varicose veins of lower extremities
Alexandra S Shadrina, Elizaveta E Elgaeva, Ian B Stanaway, Gail P Jarvik, Bahram Namjou, Wei-Qi Wei, Joe Glessner, Hakon Hakonarson, Pradeep Suri, Yakov A Tsepilov
[PloS One]
Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging
Paul RHJ Timmers, Evgeny S Tiys, Saori Sakaue, Masato Akiyama, Tuomo TJ Kiiskinen, Wei Zhou, Shih-Jen Hwang, Chen Yao, Joris Deelen, Daniel Levy, Andrea Ganna, Yoichiro Kamatani, Yukinori Okada, Peter K Joshi, James F Wilson, Yakov A Tsepilov
[Nature Aging]
Method for the Isolation of “RNA-seq-Quality” RNA from Human Intervertebral Discs after Mortar And Pestle Homogenization
Artemii A. Ivanov, Olga N. Leonova, Daniil S. Wiebe, Alexsandr V. Krutko, Mariya M. Gridina, Veniamin S. Fishman, Yurii S. Aulchenko, Yakov A. Tsepilov, Tatiana S. Golubeva
[Cells]
sumSTAAR: A flexible framework for gene-based association studies using GWAS summary statistics
Nadezhda M. Belonogova, Gulnara R. Svishcheva, Anatoly V. Kirichenko, Irina V. Zorkoltseva, Yakov A. Tsepilov, Tatiana I. Axenovich
[PLOS COMPUT BIOL]
Платформа GWAS-MAP|ovis для хранения и анализа результатов полногеномных ассоциативных исследований овец
А. В. Кириченко, А. С. Злобин, Т. И. Шашкова, Н. А. Волкова, Б. С. Иолчиев, В. А. Багиров, П. М. Бородин, Л. С. Карссен, Я. А. Цепилов, Ю. С. Аульченко
[Vavilov journal of genetics and breeding]
2021 Investigation of the causal relationships between human IgG N-glycosylation and 12 common diseases associated with changes in the IgG N-glycome
Olga O Zaytseva, Sodbo Zh Sharapov, Marcus Perola, Tonu Esko, Arianna Landini, Caroline Hayward, James F Wilson, Gordan Lauc, Yurii S Aulchenko, Lucija Klarić, Yakov A Tsepilov
[HUM MOL GENET]
Genome-wide association studies of low back pain and lumbar spinal disorders using electronic health record data identify a locus associated with lumbar spinal stenosis
Suri P, Stanaway IB, Zhang Y, Freidin MB, Tsepilov YA, Carrell DS, Williams FMK, Aulchenko YS, Hakonarson H, Namjou B, Crosslin DR, Jarvik GP, Lee MT
[PAIN]
Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function.
Shadrina AS, Zlobin AS, Zaytseva OO, Klarić L, Sharapov SZ, D Pakhomov E, Perola M, Esko T, Hayward C, Wilson JF, Lauc G, Aulchenko YS, Tsepilov YA
[HUM MOL GENET]
Nontrivial Replication of Loci Detected by Multi-Trait Methods.
Ning Z, Tsepilov YA, Sharapov SZ, Wang Z, Grishenko AK, Feng X, Shirali M, Joshi PK, Wilson JF, Pawitan Y, Haley CS, Aulchenko YS, Shen X
[Frontiers in Genetics]
Gene‑based association analysis identifes 190 genes affecting neuroticism
Nadezhda M. Belonogova IrinaV. Zorkoltseva YakovA.Tsepilov Tatiana I.Axenovich
[SCI REP-UK]
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain.
Rahman MS, Winsvold BS, Chavez Chavez SO, Børte S, Tsepilov YA, Sharapov SZ; HUNT All-In Pain, Aulchenko YS, Hagen K, Fors EA, Hveem K, Zwart JA, van Meurs JB, Freidin MB, Williams FM.
[ANN RHEUM DIS]
Multivariate Analysis Identifies Eight Novel Loci Associated with Meat Productivity Traits in Sheep
Alexander S. Zlobin Pavel S. Nikulin Natalia A. Volkova Natalia A. Zinovieva Baylar S. Iolchiev Vugar A. Bagirov Pavel M. Borodin Tatiana I. Aksenovich Yakov A. Tsepilov
[Genes]
Negative heterosis for meiotic recombination rate in spermatocytes of the domestic chicken Gallus gallus
Малиновская Любовь Петровна Тишакова Катерина Валерьевна Бикчурина Татьяна Игоревна Слободчикова Анастасия Торгунаков Никита Юрьевич Торгашева Анна Александровна Цепилов Яков Александрович Волкова Наталья Александровна Бородин Павел Михайлович
[Vavilov journal of genetics and breeding]
ОЦЕНКА ЧИСЛА ГЕНОВ, ПОЛИМОРФИЗМ КОТОРЫХ ВЛИЯЕТ НА УРОВЕНЬ НЕЙРОТИЗМА
Аксенович ТИ, Белоногова НМ, Зоркольцева ИВ, Цепилов ЯА
[Генетика]
2020 Sex- and age-specific genetic analysis of chronic back pain
Freidin M.B., Tsepilov Y.A., Stanaway I.B., Meng W., Hayward C., Smith B.H., Khoury S., Parisien M., Bortsov A., Diatchenko L., Borte S., Winsvold BS, Brumpton BM, Zwart JA, Aulchenko Y.S., Suri P., Williams F.M.K., HUNT All-In Pain
[PAIN]
Candidate genes for age at menarche are associated with endometriosis
Irina Ponomarenko, Evgeny Reshetnikov, Alexey Polonikov, Irina Verzilina, Inna Sorokina, Elizaveta E Elgaeva, Yakov A Tsepilov, Anna Yermachenko, Volodymyr Dvornyk, Mikhail Churnosov
[REPROD BIOMED ONLINE]
Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases
Klarić, Lucija Tsepilov, Yakov A. Stanton, Chloe M. Mangino, Massimo Sikka, Timo Tõnis Esko, Tõnu Pakhomov, Eugene Salo, Perttu Deelen, Joris McGurnaghan, Stuart J. Keser, Toma Vučković, Frano Ugrina, Ivo Krištić, Jasminka Gudelj, Ivan Štambuk, Jerko Plomp, Rosina Pučić-Baković, Maja Pavić, Tamara Vilaj, Marija Trbojević-Akmačić, Irena Drake, Camilla Dobrinić, Paula Mlinarec, Jelena Jelušić, Barbara Richmond, Anne Timofeeva, Maria Grishchenko, Alexander K. Dmitrieva, Julia Bermingham, Mairead L. Sharapov, Sodbo Zh. Farrington, Susan M. Theodoratou, Evropi Uh, Hae-Won Beekman, Marian Slagboom, Eline P. Louis, Edouard Georges, Michel Wuhrer, Manfred Colhoun, Helen M. Dunlop, Malcolm G. Perola, Markus Fischer, Krista Polasek, Ozren Campbell, Harry Rudan, Igor Wilson, James F. Zoldoš, Vlatka Vitart, Veronique Spector, Tim Aulchenko, Yurii S. Lauc, Gordan Hayward, Caroline
[Sci Advances]
Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions
Tsepilov Y. A., Freidin M. B., Shadrina A. S., Sharapov S. Z., Elgaeva E. E., van Zundert J., Karssen L. С., Suri P., Williams F. M. K., Aulchenko Y. S.
[Commun. biolog.]
Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies
Shadrina A. S., Shashkova T. I., Torgasheva A. A., Sharapov S. Z., Klarić L., Pakhomov E. D., Alexeev D. G., Wilson J. F., Tsepilov Y. A., Joshi P. K., Aulchenko Y. S.
[SCI REP-UK]
Replication of 15 loci involved in human plasma protein N-glycosylation in 4,802 samples from four cohorts
Sharapov SZ, Shadrina AS, Tsepilov YA, Elgaeva EE, Tiys ES, Feoktistova SG, Zaytseva OO, Vuckovic F, Cuadrat R, Jäger S, Wittenbecher C, Karssen LC, Timofeeva M, Tillin T, Trbojević-Akmačić I, Štambuk T, Rudman N, Krištić J, Šimunović J, Momčilović A, Vilaj M, Jurić J, Slana A, Gudelj I, Klarić T, Puljak L, Skelin A, Kadić AJ, Van Zundert J, Chaturvedi N, Campbell H, Dunlop M, Farrington SM, Doherty M, Dagostino C, Gieger C, Allegri M, Williams F, Schulze MB, Lauc G, Aulchenko YS.
[GLYCOBIOLOGY]
The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits
Shashkova T.I., Gorev D.D., Pakhomov E.D., Shadrina A.S., Sharapov S.Z., Tsepilov Y.A., Karssen L.C., Aulchenko Y.S.
[Vavilov journal of genetics and breeding]
2019 Defining the genetic control of human blood plasma N-glycome using genome-wide association study
Sharapov S, Tsepilov Y, Klaric L, Mangino M, Thareja G, Shadrina A, Simurina M, Dagostino C, Dmitrieva J, Vilaj M, Vuckovic F, Pavic T, Stambuk J, Trbojevic-Akmacic I, Kristic J, Simunovic J, Momcilovic A, Campbell H, Doherty M, Dunlop M, Farrington S, Pucic-Bakovic M, Gieger C, Allegri M, Louis E, Georges M, Suhre K, Spector T, Williams F, Lauc G, Aulchenko Y
[HUM MOL GENET]
Examining causal effects of body mass index on back pain: a Mendelian randomization study
Elizaveta E. Elgaeva, Yakov Tsepilov, Maxim B. Freidin, Frances M. K. Williams, Yurii Aulchenko, Pradeep Suri
[EUR SPINE J]
Identification of 12 genetic loci associated with human healthspan
Zenin A, Tsepilov Y, Sharapov S, Getmantsev E, Menshikov LI, Fedichev PO, Aulchenko Y
[Commun. biolog.]
Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals
Maxim B. Freidin, Yakov A. Tsepilov, Melody Palmer, Lennart C. Karssen, CHARGE Musculoskeletal Working Group, Pradeep Suri, Yurii S. Aulchenko, Frances M.K. Williams
[PAIN]
Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus
Malinovskaya, L. P., Tishakova, K. V., Volkova, N. A., Torgasheva, A. A., Tsepilov, Y. A., and Borodin, P. M.
[ARCH TIERZUCHT]
Male Meiotic Recombination in the Steppe Agama, Trapelus sanguinolentus (Agamidae, Iguania, Reptilia)
Lisachov A.P., Tishakova K.V., Tsepilov Y.A., Borodin P.M.
[CYTOGENET GENOME RES]
Recent advances in understanding genetic variants associated with growth, carcass and meat productivity traits in sheep (Ovis aries): an update
Zlobin, A S Volkova, N A Borodin, P M Aksenovich, T I Tsepilov, Y A
[ARCH TIERZUCHT]
Varicose veins of lower extremities: Insights from the first large-scale genetic study
Alexandra S. Shadrina, Sodbo Z. Sharapov, Tatiana I. Shashkova, Yakov A. Tsepilov
[PLOS GENET]
2018 A network-based conditional genetic association analysis of the human metabolome
Y A Tsepilov, S Z Sharapov, O O Zaytseva, J Krumsek, C Prehn, J Adamski, G Kastenmüller, R Wang-Sattler, K Strauch, C Gieger, Y S Aulchenko
[GigaScience]
Genome-wide association study in ethnic Russians suggests an association of the MHC class III genomic region with the risk of primary varicose veins
Alexandra Shadrina, Yakov Tsepilov, Ekaterina Sokolova, Mariya Smetanina, Elena Voronina, Eugene Pakhomov, Kseniya Sevost'ianova, Andrey Shevela, Evgeny Ilyukhin, Evgeny Seliverstov, Igor Zolotukhin, Maxim Filipenko
[GENE]
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
Pradeep Suri, Melody R. PalmerID, Yakov A. Tsepilov, Maxim B. Freidin,Cindy G. Boer, Michelle S. Yau, Daniel S. Evans, Andrea Gelemanovic,Traci M. Bartz, Maria Nethander, Liubov Arbeeva, Lennart Karssen, Tuhina Neogi, Archie Campbell, Dan Mellstrom, Claes Ohlsson, Lynn M. Marshall, Eric Orwoll, Andre Uitterlinden, Jerome I. Rotter, Gordan Lauc, Bruce M. Psaty, Magnus K. Karlsson, Nancy E. Lane, Gail P. Jarvik, Ozren Polasek, Marc Hochberg, Joanne M. Jordan, Joyce B. J. Van Meurs, Rebecca Jackson, Carrie M. Nielson, Braxton D. Mitchell, Blair H. Smith, Caroline Hayward, Nicholas L. Smith, Yurii S. Aulchenko, Frances M. K. Williams
[PLOS GENET]
Mycoplasma hyorhinis reduces sensitivity of human lung carcinoma cells to Nutlin-3 and promotes their malignant phenotype
Uljana A. Boyarskikh, Alexandra S. Shadrina, Mariya A. Smetanina, Yakov A. Tsepilov, Igor P. Oscorbin, Vadim V. Kozlov, Alexander E. Kel, Maxim L. Filipenko
[J CANCER RES CLIN]
Polymorphisms in inflammation-related genes and the risk of primary varicose veins in ethnic Russians
Alexandra Shadrina, Elena Voronina, Mariya Smetanina, Yakov Tsepilov, Kseniya Sevost’ianova, Andrey Shevela, Evgenii Seliverstov, Elena Zakharova, Evgeny Ilyukhin, Alexander Kirienko, Igor Zolotukhin, Maxim Filipenko
[IMMUNOL RES]
Polymorphisms of genes involved in inflammation and blood vessel development influence the risk of varicose veins
A. Shadrina , Y. Tsepilov, M. Smetanina, E. Voronina , E. Seliverstov, E. Ilyukhin, A. Kirienko ,I. Zolotukhin, M. Filipenko
[CLIN GENET]
Ассоциации полиморфизмов генов цитокинов и матриксных металлопротеиназ с минеральной плотностью костной ткани у женщин в постменопаузе с сахарным диабетом 2 типа
Фазуллина О.Н., Климонтов В.В., Коненков В.И., Шевченко А.В., Прокофьев В.Ф., Цепилов Я.А.
[Сахарный диабет]
2017 Apoptosis as the Basic Mechanism of Cytotoxic Action of Ursolic and Pomolic Acids in Glioma Cells
Frolova T.S., Lipeeva A.V., Baev D.S., Tsepilov Y. A., Sinitsyna O.I.
[Molecular Biology]
Population specific analysis of Yakut exomes
AS Zlobin, S Sh Sharapov, VP Guryev, MR Bevova, YA Tsepilov, TM Sivtseva, UA Boyarskih, EA Sokolova, YS Aulchenko, ML Filipenko, VL Osakovsky
[Doklady Biochemistry and Biophysics]
Апоптоз как основной механизм цитотоксического действия урсоловой и помоловой кислот в клетках глиомы
Фролова Т.С., Липеева А.В., Баев Д.С., Цепилов Я.С., Синицына О.И.
[Molecular Biology]
2015 NON-ADDITIVE EFFECTS OF GENES IN HUMAN METABOLOMICS
Tsepilov Y.A, Shin S., Soranzo N., Spector TD., Prehn C., Adamski J., Kastenmüller G., Wang-Sattler R., Strauch K., Gieger C., Aulchenko Y.S., Ried J.S.
[GENETICS]
2013 DEVELOPMENT AND APPLICATION OF GENOMIC CONTROL METHODS FOR GENOME-WIDE ASSOCIATION STUDIES USING NON-ADDITIVE MODELS
Yakov A. Tsepilov Janina S. Ried Konstantin Strauch Harald Grallert Cornelia M. van Duijn Tatiana I. Axenovich Yurii S. Aulchenko
[PloS One]
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