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Tuyana Malankhanova
Is not an employee of the Institute
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Publications
| 2022 |
Generation of induced pluripotent stem cell line, ICGi033-A, by reprogramming peripheral blood mononuclear cells from a patient with Huntington's disease
Grigor’eva E.V., Malakhova A.A., Sorogina D.A., Pavlova S.V., Malankhanova T.B., Abramycheva N.Yu., Klyushnikov S.A., Illarioshkin S.N., Zakian S.M.
[STEM CELL RES]
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Oxidative Stress Research on Huntington's Disease Neurons Using Genetically Encoded Biosensors
Tuyana Malankhanova, Dayaana Vasileva, Elena Grigor'eva, Sergey Medvedev, Suren Zakian, Anastasia Malakhova
[8th Scientific and Practical Conference "Biotechnology: Science and Practice"]
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| 2021 |
Creation and Research of Cell Models of Hereditary Neurodegenerative Diseases Using Directed Genome Editing
Medvedev S.P., Malankhanova T.B., Valetdinova K.R., Zakian S.M.
[NEUROCHEM J+]
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Electron microscopic analysis of autophagy in neurons
with expanded CAG repeats in the huntingtin gene in patientspecific and transgenic cell model
Lyubov Suldina, Ksenia Morozova, Tuyana Malanhanova, Anastasia Malakhova, Elena Kiseleva
[Cell Death Discovery]
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The Cutting Edge of Disease Modeling: Synergy of Induced Pluripotent Stem Cell Technology and Genetically Encoded Biosensors
Valetdinova K.R., Malankhanova T.B., Zakian S.M., Medvedev S.P.
[Biomedicines]
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Создание и исследование клеточных моделей наследственных нейродегенеративных заболеваний с помощью направленного редактирования геномов
Медведев С.П., Маланханова Т.Б., Валетдинова К.Р., Закиян С.М.
[Нейрохимия]
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| 2020 |
A Human Induced Pluripotent Stem Cell-Derived
Isogenic Model of Huntington’s Disease Based on
Neuronal Cells Has Several Relevant
Phenotypic Abnormalities
Tuyana Malankhanova, Lyubov Suldina, Elena Grigor'eva, Sergey Medvedev, Julia Minina, Ksenia Morozova, Elena Kiseleva, Suren Zakian, Anastasia Malakhova
[J. Pers. Med]
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Generation of GABAergic striatal neurons by a novel iPSC differentiation protocol enabling scalability and cryopreservation of progenitor cells
Grigor’eva E.V., Malankhanova T.B., Surumbayeva A., Pavlova S.V., Minina J.M., Kizilova E.A., Suldina L.A., Morozova K.N., Kiseleva E., Sorokoumov E.D., Lebedev I.N., Zakian S.M, Malakhova A.A.
[CYTOTECHNOLOGY]
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Generation of induced pluripotent stem cell line ICGi018-A from peripheral blood mononuclear cells of a patient with Huntington’s disease
Malakhova A.A., Grigor’eva E.V., Malankhanova T.B., Pavlova S.V., Valetdinova K.R., Abramycheva N.Yu., Vetchinova A.S., Illarioshkin S.N., Zakian S.M.
[STEM CELL RES]
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Generation of induced pluripotent stem cell lines ICGi021-A and ICGi022-A from peripheral blood mononuclear cells of two healthy individuals from Siberian population
Malakhova A.A., Grigor'eva E.V., Pavlova S.V., Malankhanova T.B., Valetdinova K.R., Vyatkin Y.V., Khabarova E.A., Rzaev J.A., Zakian S.M., Medvedev S.P.
[STEM CELL RES]
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Introducing an Expanded Trinucleotide
Repeat Tract into the Human Genome for
Huntington’s Disease Modeling In Vitro
Tuyana Malankhanova, Michael Sorokin, Sergey Medvedev, Suren Zakian, Anastasia Malakhova
[Current protocols in human genetics.]
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| 2019 |
Generation of induced pluripotent stem cell line, ICGi007-A, by reprogramming peripheral blood mononuclear cells from a patient with Huntington’s disease
Grigor’eva E.V., Malankhanova T.B., Surumbayeva A., Minina J.M., Morozov V.V., Abramycheva N.Yu., Illarioshkin S.N., Malakhova A.A., Zakian S.M.
[STEM CELL RES]
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Generation of two iPSC lines (ICGi008-A and ICGi008-B) from skin fibroblasts of a patient with early-onset Alzheimer’s disease caused by London familial APP mutation (V717I)
Grigor’eva E.V., Malankhanova T.B., Ustyantseva E.I., Minina J.M., Redina O.E., Morozov V.V., Shevela A.I., Zakian S.M, Medvedev S.P.
[STEM CELL RES]
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Исследование мутантного фенотипа изогенной клеточной модели болезни Хантингтона
Маланханова Т.Б., Григорьева Е.В., Сульдина Л.А., Морозова К.Н., Киселева Е.В., Закиян С.М., Малахова А.А.
[Гены и клетки]
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| 2018 |
Introducing an expanded CAG tract into the huntingtin gene causes a wide spectrum of ultrastructural defects in cultured human cells.
Morozova KN, Suldina LA, Malankhanova TB, Grigor'eva EV, Zakian SM, Kiseleva E, Malakhova AA.
[PloS One]
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Ultrastructural defects in isogenic lines of human cells with expanded CAG repeats in the huntingtin gene obtained via the CRISPR/Cas9 technology
K.N. Morozova, L.A. Suldina, T.B. Malankhanova, E.V. Grigor'eva, S.M. Zakian, E. Kiseleva, A.A. Malakhova
[Гены и клетки]
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| 2017 |
Modern Genome Editing Technologies in Huntington's Disease Research
Malankhanova T.B., Malakhova A.A., Medvedev S.P., Zakian S.M.
[J Huntingtons Dis.]
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Моделирование болезни Хантингтона на клетках линии HEK293
Шарипова Д.В., Маланханова Т.Б., Малахова А.А.
[Vavilov journal of genetics and breeding]
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Оптимизация инструментов геномного редактирования для получения клеточных моделей болезни Хантингтона
Маланханова Т.Б., Малахова А.А., Закиян С.М.
[Гены и клетки]
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Создание протокола направленной дифференцировки индуцированных плюрипотентных стволовых клеток человека в средние шипиковые нейроны с возможностью продолжительного культивирования и трансгенеза предшественников данных клеток
Григорьева Е.В., Маланханова Т.Б., Сурумбаева А., Павлова С.В., Малахова А.А., Закиян С.М.
[Гены и клетки]
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| 2016 |
Использование методов редактирования генома для создания изогенных клеточных линий, моделирующих болезнь Хантингтона in vitro
Малахова А.А., Сорокин М.А., Сорокина А.Е., Маланханова Т.Б., Мазурок Н.А., Медведев С.П., Закиян С.М.
[Гены и клетки]
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Стратегии редактирования паралогичных генов с помощью CRISPR/Cas9
Немудрый А.А., Маланханова Т.Б., Малахова А.А., Медведев С.П., Закиян С.М.
[Гены и клетки]
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